MEDICINAL PROPERTIES OF BITTER LEAF (VERNONIA AMYGDALINA) AND SCENT LEAF (OCIMUM GRATISSIMUM)
INTRODUCTION
Herbal medicine also called botanical medicine
or phytomedicine refers to using a plant seeds, barriers, roots, leaves, bark,
or flowers for medicinal purpose. As improvements in analysis and quality
control along with advances in clinical research show the value of herbal
medicine in the treating and preventing disease. (Ehrlich, 2009)
Medicinal plants is an important natural
resources and potentially safe drugs, plays an important role in assuaging
human health by contributing herbal medicines. The high cost of allopathic or
conventional medicine and their potential side effects encourage humans to use
traditional or herbal medicine. (Whorton, 2004).
The increasing demand of plant extracts to use
in the cosmetic, food and pharmaceutical industries suggests that systematic
studies of medicinal plants are very important in order to find active
compounds and their use as a medicine for curing various diseases. In addition,
the use of medicinal plants in developed societies have been recognized, which
can be seen by the extraction and development of several rugs and
chemotherapeutics from plants and traditionally used herbal remedies.
(Fabricant et al., 2006).
Medicinal plants are known to contain
substances which could be used for treatment purposes or used to produce drugs.
There is a rich abundance of plants reputed in traditional medicine to possess
protective and therapeutic properties. (Ibrahim et al., 2009). Many of such plants known to be used primitively to
alleviate symptoms of illnesses have been screened to have medicinal
importance, some of which are Vernonia
amygdalina (bitter leaf) and Ocimum
gratissimum (scent leaf).
Vernonia
amygdalina (bitter leaf) is a
vegetable used for preparing the popular bitter leaf soup. It is also known as Onugbu by the Igbos, Shiwaka by the Hausas and Ewuro by the Yorubas in Nigeria. As the name implies, is
actually a bitter plant whose leaves, stems, barks and extracts are used for
culinary, medicinal and curative purposes. The vitamins in bitter leaf include
vitamin A, vitamin C, vitamin E, vitamin B1 and B2. (Adaramoye et al., 2008).
Vernonia
amygdalina (bitter leaf) is a
medicinal plant of the family Asteraceae.
It is a small perennial shrub that grows in tropical Africa,
it can be propagated either by cutting or seeding. Today, the plant is widely
known throughout the continent and nearly 85% of Nigerians cultivates the plant
due to its nutritional and medicinal values. The leaves of the plant may be
consumed either as a vegetable (macerated leaves in soups) or aqueous extract
as tonics for the treatment of various illnesses. (Atangwho et al., 2007).
Ocimum
gratissimum (scent leaf or
clove basil), which is found in many tropical countries, some of its vernacula
names in Nigeria
include Ncho-anwu in Igbo, Efinrin in Yoruba, and Daidoya in Hausa. Ocimum gratissimum (scent leaf) has numerous medical uses, the oil
extracted from its leaves has been described to be active against several species
of bacteria and fungi, which also the extract is used to lower blood pressure,
strong insect repellent effects and kill many microorganisms that cause
diseases, including candida. The perennial plant Ocimum gratissimum (scent leaf), which belongs to the family
Labiatea and it is the most abundant of the genus Ocimum. (Ijeh et al., 2004).
DESCRIPTION
OF VERNONIA AMYGDALINA (BITTER LEAF) AND OCIMUM GRATISSIMUM (SCENT LEAF)
Vernonia
amygdalina is a shrub or small tree of 2-5m with petiolate
leaf of about 6cm diameter and elliptic shape. The shape leaves are green with
characteristic odour and a bitter taste, no seeds are produced and the tree is
therefore distributed through cutting. The plant grows under a range of
ecological zones in Africa and produces large
mass of forage and is drought tolerant. (Bonsi et al., 1995)
The perennial plant Ocimum gratissimum (sent leaf) is widely distributed in the tropics
of Africa and Asia. It belongs to the family labiatae and it is the most abundant of
the genus Ocimum. The plant is woody
at its base, has an average height of 1.3m high. The leaves are broad and
narrowly ovate, usually 5-13cm long and 3-9cm wide. It is a scented shrub with
lime-green fuzzy leaves. (Ijeh et al.,
2004).
MEDICINAL
IMPORTANCE OF THE PLANTS (BITTER LEAF AND SCENT)
Vernonia
amygdalina extracts may help
suppress, delay or kill cancerous cell in many ways, such as; induction of
apoptosis as determined in cell culture and animal studies, enhance
chemotherapy sensitivity, inhibition of the growth or growth signals of
cancerous cells, suppression of metastasis of cancerous cells in the body by
the inhibition of an anti-apoptotic transcription factors demonstrated in
animal studies and reduction of oestrogen level in the body by the suppression
of aromatase activity. Vernonia
amygdalina may provide an anti-oxidant benefits, man chronic diseases and
causes of food spoilage are liked to pro-oxidants, antioxidants are useful in
food preservation and drug formulations. Vernonia
amygdalina is useful in the treatment of wounds and some gastrointestinal
problems due to its antimicrobial activities. Vernonia amygdalina decreases blood glucose by 50% compared to
untreated animals. It also serves as an ingredient of cuisine, its leaf
extracts reduces low-density lipoprotein (LDL) cholesterol by 50% while also
boosting good high-density lipoprotein (HDL) cholesterol. The leaves decoction
of Vernonia amygdalina is used in the
treatment of pneumonia and increase breast milk in nursing mother, Ocimum gratissimum is used as local
medicine against leech and bilharziasis, it is also used instead of hops to
make beer in Nigeria.
The roots of Vernonia amygdalina are
useful in the treatment of tooth ache and as well as prevent gum decay due to
its bactericidal and antimicrobial activities. (Erasto et al., 2006).
The medicinal importance of scent life
includes:
Ocimum
gratissimum is extensively
used throughout West Africa as a febrifuge (fever
reducing), anti malarial and anti-coagulant. The crushed leaf juice of Ocimum gratissimum is used in the
treatment of convulsion, stomach pain, and catarrh. Oil from the leaves posses
antiseptics, antibacterial and antifungal activities. In the coastal area of Nigeria,
the plant is used in the treatment of epilepsy, high fever, and diarrhea. Ocimum gratissimum is used by the Igbos
of southern Nigeria
in the management of the baby’s cord, it is said to keep the baby’s cord and
wound surface sterile. Ocimum gratissimum
is used in the treatment of fungal infections, fever and cold. (Orafidiya et al., 2004).
HEALTH
BENEFITS OF VERNONIA AMYGDALINA (BITTER LEAF) AND OCIMUM
GRATISSIMUM (SCENT LEAF)
Vernonia
amygdalina (bitter leaf) increases the rate of metabolism in the body system
thereby improving loss of weight, contains anti-parasite, anti bacteria
properties that is needed to cure malaria, therefore serves as an anti malaria,
detoxify the blood, prevent indigestion, rheumatism, scurvy and nourishes the
skin. Regular intake of bitter leaf in diet, helps to counter the effects of
excess sugar in the blood, thereby preventing diabetes. Bitter leaf cures
common skin diseases, such as eczema, ring worms, rashes etc, by squeezing the
leaves and applying it to the affected parts. Bitter leaf juice when taken by
nursing mother, improve the quality and production breast milk, it also cures
mild stomach ailment, pile, fight liver problems and energizes the body.
Finally bitter leaf is reach source of vitamins, such as vitamin A, B1 and B2
which are needed for the body. (Ijeh et
al., 2011).
HEALTH
BENEFITS OF OCIMUM GRATISSIMUM (SCENT LEAF)
Ocimum
gratissimum (scent leaf) is
grown around houses as a mosquito repellant, and it is used for the treatment
of fever, the leaf serves as a decongestant for head colds, bronchitis and
sinusitis. The leaf is also chewed traditionally for all tooth and gum
disorders. Ocimum gratissimum promote
optimal health, rich source of anti-oxidant nutrients and helps in protection
against rheumatoid arthritis. Scent leaf is a reach source of calcium
phosphorous, iron and vitamin A, K and C. Extracts of scent leaves lowers blood
pressure, kill many micro organisms that cause disease, including candida. In Congo,
scent leaf decoction is used for diarrhea, gonorrhea infects, vaginal douches
for virginities and used in treatment of mental illness. (Ijeh et al., 2004).
USES OF THE PLANT BITTER
LEAF AND SCENT LEAF
Every part of the plants is useful; the stem,
leaves and root. The leaves are mainly used to garnish meals and prepare soups,
but other parts have medicinal benefits. Bitter leaf may be use for preparation
of soup when it is fresh or its dried form. Bitter leaf may also be used to
wash off slime from fish and snail before cooking, the stem can be used as
chewing stick, while its juice extract may be prepared for drinking. This plant
is useful in toning the vital organs of the body especially the liver and the
kidney. (Adaramoye et al., 2008).
Uses of scent leaf include:
Ocimum
gratissimum is extensively
used throughout West Africa as a febrifuge,
anti-malaria and anti-convulsant. The crushed leaf juice is used in the
treatment of convulsion, stomach pain and catarrh. The leaves are mainly used
to garnish meals and prepare soups. It can also be used as seasoning because of
its aromatic flavour. (Ijeh et al.,
2004).
ACTIVE
COMPOUNDS OF VERNONIA AMYGDALINA AND OCIMUM GRATISSIMUM
The biological-active compounds of vernonia amygadlina are saponins and
alkaloids, terpenes, steroids, coumrains, flavonoids, phenolic acids, lignans,
xanthones and anthraquinone, edotides and sesquiterpenes while that of Ocimum gratissimum are alkaloids,
tannins and flavonoids, alkaloids, terpenoids and sterols. (Erasto et al., 2006).
CONCLUSION
Plants are the major constituent of traditional
medicine, many of these plant materials such as vernonia amygdalina (bitter
leaf) and Ocimum gratissimum (scent leaf) used in herbal medicine are readily
available in rural areas and this has made it relatively cheaper than orthodox
medicine for the treatment of various disease. The upsurge in the prevalence of
side effects of many synthetic antimicrobial agents and incidence of multi-drug
resistant bacteria and pests has spurred scientist into the research for plant
based antimicrobial of therapeutic and pesticidal potentials.
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