THE EFFECTIVENESS OF DIFFERENT HAND SANITIZERS ON SOME SELECTED BACTERIA
ABSTRACT
ABSTRACT
Hand sanitizer
is formulated and used to reduce bacterial load on the skin but there have been
no previous studies on the effectiveness of this product. In this study, the
antibacterial activity of hand sanitizers was evaluated against some common
hand wash like dettol, washing soap and methylated spirit. Hand sanitizer and
methylated spirit inhibited all the micro organisms tested with highest and
least zones of inhibition against Staphylococcus
aureus (19mm) and Enterococcus
faecalis, respectively. Soap also inhibited all the organisms tested
except E. coli and Enterococcus
faecalis (10mm). This high degree of inhibition displayed by hand
sanitizer and methylated spirit is attributed to the presence of alcohol as
their major constituent, because alcohol is said to kill about 99.9% of most
bacteria. The results of this study shows that only hand sanitizer and
methylated spirit has substantial or absolute effect on the test bacteria after
contact. Therefore hand sanitizers should be used in hospital environment,
institutions, banks, hotels and religious places so as to reduce the bacteria
load on hand.
CHAPTER
ONE
1.0 INTRODUCTION
Hand washing and hand
hygiene are terms that are often used interchangeably in the general public and
among healthcare workers (HCWs). Hand hygiene is a means of making hands free
of pathogens in particular either by using water always (accompanied by soap),
hand rub or waterless sanitizers (Busari et
al., 2012). Chemicals used in hand hygiene exhibit bactericidal or
bacteriostatic properties depending on their concentrations.
Alcohol is used as the
main antibacterial component of most waterless antiseptic agents due to its
antimicrobial properties. Some alcohol-based waterless hand sanitizers (WHS)
have been reported to kill up to 99.9% of organisms within 15seconds of
application (Aiello and Larson, 2002). However, they do not possess residual
antimicrobial activity due to their high volatility. Ethanol has the record of
being the oldest skin disinfectant; it acts as a permeation enhancer when
applied topically to human skin. However, it has been reported to induce
irritation in addition to its carcinogenic properties (Lachenmeier, 2008). Hand
sanitizer wipes are not effective when hands are visibly soiled or heavily
contaminated. Hand sanitizers are well-adapted to the skin and work by
stripping away the outer layer of oil on the skin and also remove the cutaneous
micro flora (Axel et al., 2002). Hand
washing and/or the use of hand sanitizer remains the major way of breaking
transmission of infection. Different
antimicrobial agents have been incorporated into WHS to increase its
performance.WHS has been reported not only to reduce hand bacterial
contamination but also enhance hand hygiene compliance among Health Care
Workers (HCWs). Despite the widespread use of WHS in Nigeria there is dearth of information in the
open scientific literature that could substantiate its use. Therefore, this
study was aimed at investigating the antibacterial activity of commonly used
WHSs in Nigeria
on some selected common pathogenic bacteria.
1.1
STATEMENT
OF RESEARCH PROBLEM
Ordinary
soap and detergent have been known to be adequate means of removing
microorganisms and dirt from our hands and for general cleaning. But little did
the public know that there are some bacteria and viruses which could prove
stubborn to detergent and ordinary soap. The major problem is lack of
orientation and awareness campaign to the general public on the effectiveness
of hand sanitizers and mostly the wide application of hand sanitizers.
1.2
Aim
and Objectives
Aim
The
aim of this study is to determine the effectiveness of hand sanitizers.
1.3
Objectives
1. To
determine the effectiveness of hand sanitizers.
2. To
show the various areas of application of hand sanitizer.
1.4
Justification
of the study
This
study will contribute to healthy living by giving orientation to students
studying in the Federal Polytechnic Nasarawa, and enlighten the general public
on the effectiveness, areas of application and the advantage of hand sanitizer
over ordinary soap and detergent. It will help to proffer solutions to the
problems associated with the mode of transmission, prevention and control of
some deadly diseases and infections. It will serve as a reference material for
subsequent researches; the finding and recommendation will be a source of
useful information to the people.
1.5
Scope
of the study
This
project work is concerned with the study of of the effectiveness of hand
sanitizer and various areas in which they can be used.
1.6
Limitation
of the study
For
a meaningful approach of the work of this nature, one has to put into
consideration the limited time, materials and the poor general orientation and
awareness campaign to the general public.
CHAPTER
TWO
2.0
LITERATURE
REVIEW
Effectiveness of hand sanitizers
The Centers for Disease Control and
the World Health Organization says the most important way to prevent the
transmission of dangerous diseases is to frequently wash hands with soap and
water and/or use a hand sanitizer. If soap and water are not available it is
recommended to use a hand sanitizer that contains at least 60 percent alcohol
or contains a "persistent antiseptic" (Dharan et al., 2003).
Alcohol rubs kill many different kinds of bacteria, including antibiotic resistant bacteria and TB bacteria. 90% alcohol rubs also
have high virucidal activity against many different
kinds of viruses (but are highly flammable), including enveloped viruses such as the flu virus, the common cold virus, and HIV, though is notably ineffective
against the rabies virus. Alcohol rub sanitizers are not
very effective against Norovirus (winter vomiting virus) unless they
are combined with benzalkonium chloride in a hand sanitizer (Burnett, 2009).
Alcohol rubs also kill fungi. It has been reported that hand
sanitizing is more effective against fighting the common cold than hand
washing.
Alcohol kills both pathogenic microorganisms as well as resident bacterial
flora, which generally do not cause illness. Research shows that alcohol hand
sanitizers do not pose any risk by eliminating "good" microorganisms
that are naturally present on the skin. The body quickly replenishes the good
microbes on the hands, often moving them in from just up the arms where there
are fewer harmful microorganisms. However, alcohol also strips the skin of the
outer layer of oil, which may have negative effects on barrier function of the
skin. A study also shows that disinfecting hands with an antimicrobial
detergent results in a greater barrier disruption of skin compared to alcohol
solutions, suggesting an increased loss of skin lipids (Busari et al., 2012).
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